South Africa

🇿🇦 Travel Vaccinations for South Africa — City Breaks, Safaris & Coast

From Cape Town and the Garden Route to Kruger safaris and Durban’s beaches, South Africa offers incredible variety. Protect your trip with the right vaccinations and practical health advice before you fly.

At Holden’s Travel Clinics in Doncaster (DN5) and Newark (NG24), we provide same-day South Africa travel vaccines with pharmacist-led guidance tailored to your itinerary.


💉 Recommended Vaccines for South Africa

  • Hepatitis A — protection against food and water-borne infection.
  • Typhoid — recommended if eating widely, visiting townships, or travelling beyond major cities.
  • DTP booster (Tetanus, Diphtheria & Polio) — ensure your 10-year tetanus booster is up to date.
  • Rabies — advised for rural travel, safaris, trekking, cycling or animal contact (dogs, bats, monkeys, baboons).
  • Hepatitis B — important for longer trips, volunteering, medical work or potential blood exposure.

Yellow Fever: not required for direct travel from the UK. However, a certificate may be required if arriving from, or transiting over 12 hours through, a Yellow Fever risk country.

Book South Africa Travel Vaccines


🦟 Malaria & Regional Risk

Most of South Africa is malaria-free. Risk exists mainly in the lowveld regions bordering Mozambique and Zimbabwe — including parts of Mpumalanga, Limpopo, and the Kruger National Park.

  • Antimalarial tablets recommended for visits to malaria zones — ask us during your consultation.
  • Use repellent (DEET/picaridin), long sleeves after dusk, and bed nets where available.

🌡️ General Health & Safety

  • Food & water: choose reputable restaurants; avoid untreated water in rural areas.
  • Sun & heat: South Africa has high UV — use SPF 30+, stay hydrated, and take electrolytes if hiking.
  • Wildlife: follow reserve rules — avoid feeding or approaching animals, especially baboons.

✈️ When to Book

Book vaccines 2–4 weeks before departure. We also support last-minute travellers with express appointments.

Our clinics serve Doncaster, Newark and surrounding areas including Scawsby, Cusworth, Bentley, Balderton and wider South Yorkshire & Nottinghamshire.

Book Your Appointment


📍 Visit Holden’s Travel Clinics

Doncaster (DN5)

Holden’s Chemist Express, Scawsby
Unit 4, Barnsley Road, Doncaster, DN5 8QE

  • Walk-in & same-day appointments
  • All major travel vaccines
  • Full documentation & certificates
  • Pharmacist-led travel health advice

Newark (NG24)

Holden’s Chemist, Newark
Eton Avenue, Newark, NG24

  • Convenient local travel vaccine service
  • Same-day & short-notice appointments
  • Friendly, expert clinical support

Book Now